ERITROCITOSIS PATOLÓGICA DE ALTURA: Caracterización biológica, diagnóstico y tratamiento. HIGH ALTITUDE PATHOLOGICAL ERYTHROCYTOSIS. Diagnóstico y tratamiento | 23 DIC Eritrocitosis. Actualización de los métodos diagnósticos y el manejo de los pacientes con eritrocitosis. 3. original research. DOI: Secondary erythrocytosis due to hypoxemia as prognosis. in exacerbated chronic .

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Revista de la Facultad de Medicina

Br J Dis Chest ; The variables that were statistically significant showed some unusual associations, particularly with the Anthonisen classification and the presence of a history of trqtamiento failure, the latter being a protective factor, without defining a coherent explanation for this finding and without any publication report with a similar result that could be used to infer that protective effect.

Spleen sizing by ultrasound in polycythaemia and thrombocythaemia: History of heart failure. There are several observations that have found a worse prognosis of mortality and need for hospitalization in patients with lower red cell mass compared to those with higher values 9,10, After checking the study entry criteria and obtaining the authorization of the patients or caregiver for inclusion, we proceeded to collect information through a survey to patients during their hospital stay.

Conflict of interests None stated by the tratamiennto. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Demographic, clinical and paraclinical characteristics of patients included in the study. Variables were described using an additional categorization by hematocrit levels and an adjustment in a multivariate model through logistic regression.

The prognostic value of this variable in the exacerbation has not been evaluated to date. This research could not determine any relationship between erythrocyte parameters and prognosis of patients suffering from pulmonary diseases; nevertheless, extreme values of hematocrits tended to have adverse outcomes.


Study assessments After checking the study entry criteria and obtaining the authorization of the patients or caregiver for inclusion, we proceeded to collect information through a survey to patients during their hospital stay.

The following operating variables were established as admission and results analysis criteria:. Am Heart J ; Am J Med ; In long-term observations, anemia has been identified as a factor involved in the development of adverse events in patients with stable chronic lung disease, whereas erythrocytosis has shown its inference on a better prognosis Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema: The multivariate analysis did not include erythrocyte parameters given the lack of statistical significance of the data provided by these variables with the outcome.


Br J Haematol ; Phlebotomy was performed in only three patients; indications focused on tratakiento hematocrit value and the technique used was variable in each case without having a direct relationship between the volume of blood extracted and the change of red cell values, in fact, in one patient no changes were seen.

Tratamienro erythrocytosis due to hypoxemia as prognosis in exacerbated chronic pulmonary diseases. Different variables have been decisive for the prognosis of exacerbations; however, despite the pathophysiological correlation between chronic lung diseases with hypoxemia and erythrocytosis development, red blood cell parameters have not been evaluated as predictors of these events 2,5. Bivariate analysis of tratakiento factors for the composite outcome. Therefore, there is a big gap in the state of the art, which indicates the need to expand clinical research to achieve a better characterization of the risk and the need for treatment of secondary erythrocytosis in stable and exacerbated chronic lung disease.

Another limitation of the study was establishing definitions accepted for inclusion criteria and data analysis. By contrast, other prognostic factors found to be related with exacerbations in other studies, tratmaiento as age, use of home oxygen, the presence of signs of respiratory distress at admission, the number of Anthonisen criteria trxtamiento and blood gases, could not be validated in this cohort 2,5,22,23, Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD.

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These data, although eritrocitosia, revalidated the limitation on the approach to a patient with erythrocytosis in the emergency room, as well as the absence of protocols that clarify the possible indications and phlebotomy techniques. The effects of therapeutic decrease in packed cell volume on the responses to exercise of patients with polycythaemia secondary to lung disease.

Erythrocyte parameters showed an overall predilection of being within normal values, with a median of Patients with congenital heart disease, for whom diagnosis of exacerbation of lung disease was discarded at discharge, and those who did not wish erritrocitosis participate in the study were excluded from the study.

In-hospital mortality following acute exacerbations of chronic obstructive pulmonary disease. The cohort was composed by subjects with a minimum age of 43 and a maximum age of 90, for a median of Thus, determining the implications of erythrocyte parameters might contribute to define the usefulness of phlebotomy or red blood cells transfusion in these patients.

Effects of theophylline on erythropoietin production in normal subjects and in patients with erythrocytosis after renal transplantation. Asthma cases had an exclusive distribution in women.

Regarding red blood cell parameters, a tendency to have a protective effect when located in the core values of hematocrit against extreme values, this difference did not show a statistical significance. Chronic obstructive tratwmiento disease. Cochrane Database Syst Rev ;4: